There are a variety of formation mechanisms for the different types of nebulae. Some nebulae form from gas that is already in the interstellar medium while others are produced by stars. Examples of the former case are giant molecular clouds, the coldest, densest phase of interstellar gas, which can form by the cooling and condensation of more diffuse gas. Examples of the latter case are planetary nebulae formed from material shed by a star in late stages of its stellar evolution.
Star-forming regions are a class of emission nebula associated with giant molecular clouds. These form as a molecular cloud collapses under its own weight, producing stars. Massive stars may form in the center, and their ultraviolet radiation ionizes the surrounding gas, making it visible at optical wavelengths. The region of ionized hydrogen surrounding the massive stars is known as an H II region while the shells of neutral hydrogen surrounding the H II region are known as photodissociation region. Examples of star-forming regions are the Orion Nebula, the Rosette Nebula and the Omega Nebula.

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