After graduating from Harvard, Holmes entered the Dane Law School at Cambridge. He did not feel at all sure, however, that he wished to be a lawyer, and at the end of a year he had so far lost interest in his studies that he gave them up. As the physician's calling seemed much more to his liking, he took two courses of study in a private school of medicine. This preparation was not, of course, sufficient to fit him for a larger practice, so a trip to Europe where he could study under the great professors of the School of Medicine at Paris became necessary. Accordingly, his parents, at some sacrifice to themselves, provided him with the required means, and he set sail from New York in the spring of 1833.
During the two years spent abroad, Holmes gave himself up wholly to his chosen study. "I am more and more attached every day to the study of my profession.... I am occupied from morning to night, and as every one is happy when he is occupied, I enjoy myself as much as I could wish," he wrote home.

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